Chloroplasts evolved an additional layer of translational regulation based on non-AUG start codons for proteins with different turnover rates.

ABSTRACT: Chloroplasts have evolved from photosynthetic cyanobacteria-like progenitors through endosymbiosis. The chloroplasts of present-day land plants have their own transcription and translation systems that show several similarities with prokaryotic organisms. A remarkable feature of the chloroplast translation system is the use of non-AUG start codons in the protein synthesis of certain genes that are evolutionarily conserved from Algae to angiosperms. However, the biological significance of such use of non-AUG codons is not fully understood. The present study was undertaken to unravel the significance of non-AUG start codons in vivo using the chloroplast genetic engineering approach. For this purpose, stable transplastomic tobacco plants expressing a reporter gene i.e. uidA (GUS) under four d

SUBMITTER: Sadhu L 

PROVIDER: S-EPMC9845219 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature