Comparative expression analysis in three Brassicaceae species revealed compensatory changes of the underlying gene regulatory network

ABSTRACT: Trichomes are regularly distributed on the leaves of Arabidopsis thaliana. The gene regulatory network underlying trichome patterning involves more than 15 genes. However, it is possible to explain patterning with only five components. This raises the questions about the function of the additional components and the identification of the core network. In this study, we compare the relative expression of all patterning genes in A. thaliana, A. alpina and C. hirsuta by qPCR analysis and use mathematical modelling to determine the relative importance of patterning genes. As the involved proteins exhibit evolutionary conserved differential complex formation, we reasoned that the genes belonging to the core network should exhibit similar expression ratios in different species. However, we find

SUBMITTER: Pietsch J 

PROVIDER: S-EPMC9845631 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature