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The potential interaction between medical treatment and radioiodine treatment success: A systematic review.


ABSTRACT:

Introduction

Radioactive iodine (RAI) therapy is a critical component in the post-surgical management of thyroid cancer patients, as well as being a central therapeutic option in the treatment of hyperthyroidism. Previous work suggests that antithyroid drugs hinder the efficacy of RAI therapy in patients. However, the effects of other background medications on RAI treatment efficacy have not been evaluated. Therefore, we performed a systematic review and meta-analysis investigating the potential off-target effects of medication on RAI therapy in patients with thyroid cancer and hyperthyroidism.

Methods

Systematic review and meta-analysis according to the 2020 PRISMA guidelines. Databases searched: MEDLINE, EMBASE and Cochrane Library for studies published between 2001 and 20

SUBMITTER: Zannat R 

PROVIDER: S-EPMC9845773 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature