Triglyceride-glucose index and the incidence of stroke: A meta-analysis of cohort studies.

ABSTRACT:

Background

Insulin resistance (IR) is involved in the pathogenesis of atherosclerosis. As a new indicator, the triglyceride-glucose (TyG) index has greater operability for the evaluation of insulin resistance. Previous studies have shown inconsistent results in evaluating the association between the TyG index and stroke incidence in people without stroke at baseline. Therefore, this study aimed to systematically assess this association through a meta-analysis.

Methods

Cohort studies with the multivariate-adjusted hazard ratio (HR) association between the TyG index and stroke were obtained by searching the PubMed, Cochrane Library, and EMBASE databases before 16 December 2021. We pooled the adjusted HR along with 95% CI using a random-effects model. The primary outcome was st

SUBMITTER: Liao C 

PROVIDER: S-EPMC9845890 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature