Depressive symptoms predict longitudinal changes of chronic inflammation at the transition to adulthood.

ABSTRACT:

Background

Inflammation is closely related to poor mental and physical health, including depressive symptoms and its specific symptoms. To reveal the linear and nonlinear relationships between depressive symptoms and chronic inflammation levels, and perform further analysis of the associations between symptom-specificity of depressive symptoms and inflammation among young adults by using a prospective design.

Methods

In this longitudinal study, we examined college students recruited from two universities in China, who were examined at baseline and 2-years follow-up. Depressive symptoms were measured by applying the Patient Health Questionnaire 9 (PHQ-9) at baseline. Plasma levels of four inflammatory biomarkers, including interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor n

SUBMITTER: Zhai S 

PROVIDER: S-EPMC9846044 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature