The correlation of Th22 and regulatory T cells with Helicobacter pylori infection in patients with chronic gastritis.

ABSTRACT:

Objective

Helicobacter pylori is planted in the human stomach and is the most common cause of chronic gastritis, which produced specific local and systemic humoral immunity, while the associations of these immune responses and H. pylori in the development of chronic gastritis remain unclear.

Methods

This study analyzed histology, the number of Th22 and regulatory T (Treg) cells, and the levels of inflammation- and gastritis-related indicators between 22 H. pylori-infected and 24 non-H. pylori-infected chronic gastritis patients by hematoxylin-eosin staining, enzyme-linked immunosorbent assay, quantitative reverse transcription PCR, and flow cytometry analysis.

Results

This study found that the pathological damage degree of gastric mucosa in H. pylori infection patient

SUBMITTER: Yao B 

PROVIDER: S-EPMC9846114 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature