Communicating PNPLA3 genetic risk status for NAFLD among Mexican-origin men.

ABSTRACT:

Introduction

The burden of non-alcoholic fatty liver disease (NAFLD) continues to disproportionately impact under-resourced communities in the U.S., particularly Mexican-origin populations. Genetic polymorphisms such as the rs738409 C/G variant in patatin-like phospholipase domain-containing 3 (PNPLA3) have been associated with higher prevalence of and progression along the NAFLD spectrum. This qualitative study conducted in the U.S. Southwest aimed to assess Mexican-origin men's experience receiving genetic testing for PNPLA3 risk carrier status.

Methods

Semi-structured interviews were conducted with 17 Mexican-origin men whose NAFLD status and genetic predisposition were determined as part of a previous cross-sectional study. The interview guide included ques

SUBMITTER: Villavicencio EA 

PROVIDER: S-EPMC9846364 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature