Abnormal functional connectivity of the frontostriatal circuits in type 2 diabetes mellitus.

ABSTRACT:

Background

Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with an increased incidence of cognitive and emotional disorders. Previous studies have indicated that the frontostriatal circuits play a significant role in brain disorders. However, few studies have investigated functional connectivity (FC) abnormalities in the frontostriatal circuits in T2DM.

Objective

We aimed to investigate the abnormal functional connectivity (FC) of the frontostriatal circuits in patients with T2DM and to explore the relationship between abnormal FC and diabetes-related variables.

Methods

Twenty-seven patients with T2DM were selected as the patient group, and 27 healthy peoples were selected as the healthy controls (HCs). The two groups were matched for age and sex. I

SUBMITTER: Fu Y 

PROVIDER: S-EPMC9846649 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature