Beauveria bassiana interacts with gut and hemocytes to manipulate Aedes aegypti immunity.

ABSTRACT:

Background

Mosquito-borne diseases affect millions of people. Chemical insecticides are currently employed against mosquitoes. However, many cases of insecticide resistance have been reported. Entomopathogenic fungi (EPF) have demonstrated potential as a bioinsecticide. Here, we assessed the invasion of the EPF Beauveria bassiana into Aedes aegypti larvae and changes in the activity of phenoloxidase (PO) as a proxy for the general activation of the insect innate immune system. In addition, other cellular and humoral responses were evaluated.

Methods

Larvae were exposed to blastospores or conidia of B. bassiana CG 206. After 24 and 48 h, scanning electron microscopy (SEM) was conducted on the larvae. The hemolymph was collected to determine changes in total hemocyte concentra

SUBMITTER: de Oliveira Barbosa Bitencourt R 

PROVIDER: S-EPMC9847134 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature