Trajectories of depression symptoms in a therapist-supported digital mental health intervention: a repeated measures latent profile analysis.

ABSTRACT:

Purpose

Major depression affects 10% of the US adult population annually, contributing to significant burden and impairment. Research indicates treatment response is a non-linear process characterized by combinations of gradual changes and abrupt shifts in depression symptoms, although less is known about differential trajectories of depression symptoms in therapist-supported digital mental health interventions (DMHI).

Methods

Repeated measures latent profile analysis was used to empirically identify differential trajectories based upon biweekly depression scores on the Patient Health Questionnaire-9 (PHQ-9) among patients engaging in a therapist-supported DMHI from January 2020 to July 2021. Multivariate associations between symptom trajectories with sociodemographics and c

SUBMITTER: Peiper NC 

PROVIDER: S-EPMC9847436 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature