Colorimetric and photothermal dual-mode lateral flow immunoassay based on Au-Fe₃O₄ multifunctional nanoparticles for detection of Salmonella typhimurium.

ABSTRACT: Au-Fe₃O₄ multifunctional nanoparticles (NPs) were synthesized and integrated with lateral flow immunoassay (LFIA) for dual-mode detection of Salmonella typhimurium. The Au-Fe₃O₄ NPs not only combined excellent local surface plasmon resonance characteristics and superparamagnetic properties, but also exhibited good photothermal effect. In the detection, antibody-conjugated Au-Fe₃O₄ NPs first captured S. typhimurium from complex matrix, which was then loaded on the LFIA strip and trapped by the T-line. By observing the color bands with the naked eyes, qualitative detection was performed free of instrument. By measuring the photothermal signal, quantification was achieved with a portable infrared thermal camera. The introductio

SUBMITTER: Wen CY 

PROVIDER: S-EPMC9847459 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature