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Plain metallic biomaterials: opportunities and challenges.


ABSTRACT: The 'plainification of materials' has been conceptualized to promote the sustainable development of materials. This perspective, for the first time in the field of biomaterials, proposes and defines 'plain metallic biomaterials (PMBs)' with demonstrated research and application case studies of pure titanium with high strength and toughness, and biodegradable, fine-grained and high-purity magnesium. Then, after discussing the features, benefits and opportunities of PMBs, the challenges are analyzed from both technical and regulatory aspects. Regulatory perspectives on PMB-based medical devices are also provided for the benefit of future research, development and commercialization.

SUBMITTER: Zhang J 

PROVIDER: S-EPMC9847527 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Plain metallic biomaterials: opportunities and challenges.

Zhang Jiazhen J   Zhai Bao B   Gao Jintao J   Li Zheng Z   Zheng Yufeng Y   Ma Minglong M   Li Yongjun Y   Zhang Kui K   Guo Yajuan Y   Shi Xinli X   Liu Bin B   Gao Guobiao G   Sun Lei L  

Regenerative biomaterials 20221115


The 'plainification of materials' has been conceptualized to promote the sustainable development of materials. This perspective, for the first time in the field of biomaterials, proposes and defines 'plain metallic biomaterials (PMBs)' with demonstrated research and application case studies of pure titanium with high strength and toughness, and biodegradable, fine-grained and high-purity magnesium. Then, after discussing the features, benefits and opportunities of PMBs, the challenges are analyz  ...[more]

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