The association between serum orexin A and short-term neurological improvement in patients with mild to moderate acute ischemic stroke.

ABSTRACT:

Background

The serum orexin A level was significantly lower among patients with acute ischemic stroke (AIS) and negatively related to the volume of the infarction, but the relationship between serum orexin A and prognosis of AIS was still unclear. We aimed to clarify the association between serum orexin A and the short-term neurological improvement in patients with mild to moderate AIS.

Methods

We consecutively enrolled patients with first ever mild to moderate AIS admitted to hospital within 48 h from symptom onset in this prospective observational study. The serum orexin A concentrations were determined on the second morning since the admission. The short-term neurological improvement was defined as more than 1 point decrease in the National Institute of Health Stroke Scal

SUBMITTER: Hu S 

PROVIDER: S-EPMC9847589 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature