Meta-analysis of peripheral insulin-like growth factor 1 levels in schizophrenia.

ABSTRACT:

Objective

We aimed to investigate if there is a significant difference in peripheral insulin-like growth factor 1 (IGF-1) levels between schizophrenia patients and healthy controls and to determine whether a difference exists before and after initiation of antipsychotics.

Methods

PubMed/MEDLINE, Scopus, and Web of Science were searched up to March 27, 2022. Original clinical studies of any type that reported peripheral blood, serum or plasma IGF-1 levels measured after fasting in schizophrenia patients and/or healthy control group were selected based on inclusion and exclusion criteria. Data were analyzed using Meta-Essentials: Workbooks for meta-analysis and pooled through random-effects meta-analyses.

Results

Twelve publications met eligibility criteria. Schizophren

SUBMITTER: Pejcic AV 

PROVIDER: S-EPMC9847627 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature