Signatures and prognostic values of related immune targets in tongue cancer.

ABSTRACT:

Background

Tongue cancer, as one of the most malignant oral cancers, is highly invasive and has a high risk of recurrence. At present, tongue cancer is not obvious and easy to miss the opportunity for early diagnosis when in the advanced stage. It is important to find markers that can predict the occurrence and progression of tongue cancer.

Methods

Bioinformatics analysis plays an important role in the acquisition of marker genes. GEO and TCGA data are very important public databases. In addition to expression data, the TCGA database also contains corresponding clinical data. In this study, we screened three GEO data sets that met the standard, which included GSE13601, GSE34105, and GSE34106. These data sets were combined using the SVA package to prepare the data for differe

SUBMITTER: Lv X 

PROVIDER: S-EPMC9848309 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature