Serum vitamin levels in multiple system atrophy: A case-control study.

ABSTRACT:

Aim

There is increasing evidence suggesting that vitamins may play important roles in the pathogenesis of multiple system atrophy (MSA). The purpose of this study was to detect the changes of serum vitamin levels and investigate their correlation with disease severity in MSA patients.

Methods

In this cross-sectional study, 244 MSA patients, 200 Parkinson's disease (PD) patients and 244 age-gender matched healthy controls were recruited. Serum vitamin levels were measured, including vitamin A, B1, B2, B9 (folate), B12, C, D, and E. Relevant clinical scales were used to assess the disease severity of MSA patients.

Results

Compared with the healthy controls, decreased serum folate levels and increased serum vitamin A and C levels were detected in MSA patients. Similar di

SUBMITTER: Chen D 

PROVIDER: S-EPMC9849558 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature