HAS-BLED vs. ORBIT scores in anticoagulated patients with atrial fibrillation: A systematic review and meta-analysis.

ABSTRACT:

Background

The 2021 UK National Institute for Health and Care Excellence guidelines tend to recommend the ORBIT score for predicting bleeding risk in patients with atrial fibrillation (AF) with anticoagulants. Herein, we comprehensively re-assessed the predicted abilities of the HAS-BLED vs. ORBIT score since several newly published data showed different findings.

Methods

We comprehensively searched the PubMed electronic database until December 2021 to identify relevant studies reporting the ORBIT vs. HAS-BLED scores in anticoagulated patients with AF. Their predicted abilities were assessed using the C-index, reclassification, and calibration analysis.

Results

Finally, 17 studies were included in this review. In the pooled analysis, the ORBIT score had a C-index of 0

SUBMITTER: Liu X 

PROVIDER: S-EPMC9849745 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature