Are adrenergic α1- antagonists beneficial for the access of retrograde ureteral access sheath or semi-rigid ureteroscope access? A systematic review and meta-analysis.

ABSTRACT:

Introduction

To evaluate the clinical benefit of preoperative adrenergic α1-antagonist therapy in the management of upper urinary calculi.

Materials and methods

Publications were searched for The Cochrane Central Register of Controlled Trials, EMBASE, and MEDLINE until 1 March 2022 that related to the adrenergic α1- antagonist intake as adjunctive therapy before retrograde surgery. Dichotomous data were reported with risk ratios (RR) with 95% confidence intervals (CIs) and the continuous data were reported with mean difference (MD) with 95% CIs.

Results

There were nine studies with 867 patients included in this meta-analysis. Preoperative adrenergic α1- antagonists could significantly elevate the compared with the placebo. Higher successful access rate to the stone wa

SUBMITTER: Hu Q 

PROVIDER: S-EPMC9849750 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature