Risk of dementia according to the severity of chronic periodontitis in Korea: a nationwide retrospective cohort study.

ABSTRACT:

Objectives

We investigated the risk of dementia in older adults with chronic periodontitis according to the severity of periodontitis.

Methods

Data on patients with chronic periodontitis were extracted from the National Health Insurance Service-Senior cohort database from 2002 to 2014. Among 52,728 subjects eligible for inclusion, 11,953 subjects had newly diagnosed mild chronic periodontitis (MCP), and 40,775 subjects had newly diagnosed severe chronic periodontitis (SCP). Two 1:1 propensity score matched cohorts were created with 8,624 patients each in the MCP and SCP groups. To analyze the risk of dementia, a Cox proportional-hazard model was used to calculate hazard ratios with 95% confidence intervals (CIs).

Results

In the Kaplan-Meier curve, the disease-free pro

SUBMITTER: Kim SR 

PROVIDER: S-EPMC9849849 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature