The impact of etiology in lesion-symptom mapping - A direct comparison between tumor and stroke.

ABSTRACT:

Introduction

Lesion-symptom mapping is a key tool in understanding the relationship between brain structures and behavior. However, the behavioral consequences of lesions from different etiologies may vary because of how they affect brain tissue and how they are distributed. The inclusion of different etiologies would increase the statistical power but has been critically debated. Meanwhile, findings from lesion studies are a valuable resource for clinicians and used across different etiologies. Therefore, the main objective of the present study was to directly compare lesion-symptom maps for memory and language functions from two populations, a tumor versus a stroke population.

Methods

Data from two different studies were combined. Both the brain tumor (N = 196) and stroke

SUBMITTER: van Grinsven EE 

PROVIDER: S-EPMC9850191 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature