Characteristics and predictors of short-term mortality in decompensated cirrhotic patients with acute-on-chronic liver failure.

ABSTRACT:

Aim of the study

We aimed to investigate the characteristics of acute-on-chronic liver failure (ACLF) and factors associated with 28-day mortality in patients with ACLF.

Material and methods

This prospective study included ACLF patients based on the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) Consortium criteria, admitted between March 2021 and February 2022. We examined variables associated with 28-day mortality using multivariate Cox regression analysis.

Results

Of 326 patients admitted with acute decompensation (AD) of cirrhosis, 109 (33.44%) patients were diagnosed with ACLF (mean age 63.61 ±11.15 years, 65.14% males). Of these, 26.61%, 35.78%, and 37.61% of patients were in ACLF grades 1, 2, and 3 respectively. HCV (80.73%) w

SUBMITTER: Abudeif A 

PROVIDER: S-EPMC9850305 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature