In situ synthesis of polythiophene encapsulated 2D hexagonal boron nitride nanocomposite based electrochemical transducer for detection of 5-fluorouracil with high selectivity.

ABSTRACT: It is difficult for the scientific community to develop a nonenzymatic sensing platform for extremely sensitive and selective detection of specific biomolecules, antibiotics, food adulterants, heavy metals, etc. One of the most significant chemotherapy drugs, 5-fluorouracil (5-Fu), which is used to treat solid malignancies, has a fluorine atom in the fifth position of the uracil molecule. Recognizing the secure and effective dosing of drugs for chemotherapy continues to be a critical concern in cancer disease management. The maintenance of the optimal 5-Fu concentration is dependent on the presence of 5-Fu in biofluids. Herein we reported a conducting polymer encapsulated 2D material, PTh/h-BN for the efficient electrochemical detection of anticancer drug 5-Fu. Furthermore, the synt

SUBMITTER: Muthukumaran MK 

PROVIDER: S-EPMC9850362 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature