Improvement of Hyperthermia Properties of Iron Oxide Nanoparticles by Surface Coating.

ABSTRACT: Magnetic hyperthermia is an oncological therapy that exploits magnetic nanoparticles activated by radiofrequency magnetic fields to produce a controlled temperature increase in a diseased tissue. The specific loss power (SLP) of magnetic nanoparticles or the capability to release heat can be improved using surface treatments, which can reduce agglomeration effects, thus impacting on local magnetostatic interactions. In this work, Fe₃O₄ nanoparticles are synthesized via a coprecipitation reaction and fully characterized in terms of structural, morphological, dimensional, magnetic, and hyperthermia properties (under the Hergt-Dutz limit). Different types of surface coatings are tested, comparing their impact on the heating efficacy and colloidal stability, resulting tha

SUBMITTER: Vassallo M 

PROVIDER: S-EPMC9850460 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature