Efficacy of three sputum specimens for the diagnosis of Mycobacterium avium complex pulmonary disease.

ABSTRACT:

Background

In Mycobacterium avium complex pulmonary disease (MAC-PD), diagnosis requires a positive culture from at least two separate expectorated sputum specimens. The optimal number of sputum examinations remains unclear.

Objective

This study sought to elucidate the diagnostic yield of acid-fast bacilli in MAC-PD using 3 sputum specimens and to clarify the clinical characteristics of patients with MAC-PD diagnosed using 3 sputum specimens. Furthermore, we investigated the correlation between increased number of sputum specimens and diagnostic yield.

Methods

We reviewed the medical records of 139 patients with MAC-PD diagnosed at Toho University Omori Medical Center for whom at least three sputum specimens were examined before treatment from November 2014 through Ju

SUBMITTER: Urabe N 

PROVIDER: S-EPMC9850505 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature