Optimized protocol for double vaccine immunization against classical swine fever and porcine reproductive and respiratory syndrome.

ABSTRACT:

Background

Classical swine fever and porcine reproductive and respiratory syndrome have seriously affected the development of the swine breeding industry in China. Vaccine immunization remains the main way to prevent these infections. The aim of this study was to establish an optimized protocol for vaccine immunization against classical swine fever virus (CSFV) and porcine reproductive and respiratory syndrome virus (PRRSV).

Methods

Blood samples were collected from the anterior vena cava of pigs after immunization, and blood indices, secreted levels of specific antibodies and neutralizing antibodies associated with humoral immunity, the proliferation capacity of T lymphocytes as a measure of cellular immunity, and secreted levels of IFN-γ and TNF-α were determined.

Resul

SUBMITTER: Liu Z 

PROVIDER: S-EPMC9850545 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature