Serum 25-hydroxyvitamin D is associated with stroke history in a reverse J-shape.

ABSTRACT:

Background

25-hydroxyvitamin D [25(OH)D], the major form of vitamin D in the body, has a non-linear association with stroke risk. However, the association is not fully understood. The specific shape of the association and the ideal value of 25(OH)D related to minimum risk of stroke remain unclear.

Aim

We conducted the study to establish the correlation between circulating 25(OH)D and stroke history and determine the ideal value of 25(OH)D in relation to the lowest stroke prevalence.

Methods

Data from the National Health and Nutrition Examination Survey (NHANES) were used for analyzes. We used multivariate logistic regression analysis with fitted smooth curves to explore the relationship between 25(OH)D and self-reported stroke history. Subsequently, 40,632 participant

SUBMITTER: Pan JH 

PROVIDER: S-EPMC9851395 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature