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Rectal MRI Interpretation After Neoadjuvant Therapy.


ABSTRACT: In recent years, several key advances in the management of locally advanced rectal cancer have been made, including the implementation of total mesorectal excision as the standard surgical approach; use of neoadjuvant chemoradiotherapy in selected patients with a high risk of local recurrence, and finally, adoption of organ preservation strategies, through either local excision or nonoperative management in selected patients with clinical complete response following neoadjuvant chemoradiotherapy. This review aims to shed light on the role of rectal MRI in the assessment of treatment response after neoadjuvant therapy, which is especially important given the growing feasibility of nonoperative management. First, an overview of current neoadjuvant therapies and response assessment based on d

SUBMITTER: Horvat N 

PROVIDER: S-EPMC9851947 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature