Retrospective analyses of clinical features in 28 Chinese patients with type V osteogenesis imperfecta: new perspectives in an old issue.

ABSTRACT: Type V osteogenesis imperfecta (OI) is a form of OI characterized by radial head dislocation (RHD), calcification of interosseous membrane (CIM), and hyperplastic callus (HPC). In this study, we characterized the clinical features of 28 type V OI patients. We presented that dysfunctions of elbow, hip joint, and abnormal epiphyseal growth plate were associated with ectopic calcification and summarized the history of HPC progression and treatment.

Introduction

The current study aims to systematically characterize the skeletal phenotypes of patients with type V OI and suggested possible surgical solutions.

Methods

A total of 28 patients were admitted for inpatient care at The Hong Kong University-Shenzhen Hospital diagnosed with type V OI (either clinically diagnosed or genetica

SUBMITTER: Tan Z 

PROVIDER: S-EPMC9852172 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature