Epidural esketamine and morphine for postoperative analgesia after caesarean delivery: A pilot study.

ABSTRACT:

Objective

The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after cesarean section.

Methods

Parturients who planned for a cesarean delivery using combined spinal-epidural anesthesia with a request for postoperative anesthesia were randomly divided into four groups (A, B, C, and D). When the surgery was completed, the parturients in groups A, B, C, and D were administered 2 mg morphine, 0.25 mg/kg of esketamine, 0.25 mg/kg of esketamine plus 2 mg morphine hydrochloride, and 0.25 mg/kg of esketamine plus 1 mg morphine through the epidural catheters, respectively. The postoperative pain at rest, pain with movement, the number of rescue analgesics, and adverse effects were evaluated for 48 h after cesarean

SUBMITTER: Tang J 

PROVIDER: S-EPMC9852529 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature