An evaluation of the Index4 tool for chemotherapy toxicity prediction in cancer patients older than 70 years old.

ABSTRACT: Chemotherapy, although beneficial for improving outcomes in both localized and metastatic cancers, may be associated with significant adverse effects, especially for patients with decreased functional reserves. Prediction of patients who will not tolerate well chemotherapy treatment may help in modifying treatment plans and in reallocating resources to vulnerable patients. One hundred seventeen consecutive cancer patients over the age of 70 scheduled for chemotherapy treatment in a single cancer center were included in the study. Prediction of adverse chemotherapy outcomes were calculated using a prediction tool proposed and validated from the Cancer and Aging Research Group (CARG) and a prediction tool proposed by us, called Index4. The 2 tools were compared for their ability to predict g

SUBMITTER: Lewis A 

PROVIDER: S-EPMC9852555 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature