Risk factors for distant metastasis and prognosis in stage T1 esophageal cancer: A population-based study.

ABSTRACT:

Purpose

Stage T1 esophageal cancer (EC) with distant metastasis (DM) is rare and poorly understood. In this study, we aimed to construct and validate a novel nomogram for predicting the probability of DM in T1 EC patients.

Methods

A total of 1,663 eligible T1 EC patients were enrolled from the Surveillance, Epidemiology, and End Results (SEER) database between 2004 and 2015. The patients were randomly divided into training and validation cohorts. Univariate and multivariate logistic analyses in the training cohort were used to identify risk factors related to DM, and then these risk factors were applied to construct the nomogram. Receiver operating characteristic (ROC) curves, the area under the curve (AUC), calibration plots, the Hosmer-Lemeshow (HL) test, and decision curv

SUBMITTER: Zhu K 

PROVIDER: S-EPMC9852716 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature