Maternal diet associated with infants' intestinal microbiota mediated by predominant long-chain fatty acid in breast milk.

ABSTRACT:

Introduction

Long-chain fatty acids in breast milk are affected by the mother's diet and play an important role in the growth, development, and immune construction of infants. This study aims to explore the correlation between maternal diet, breast milk fatty acids (FAs), and the infant intestinal flora.

Methods

We enrolled 56 paired mothers and their infants; both breast milk samples and infants' fecal samples were collected to determine the long-chain FA content of breast milk by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS), and metagenomic technology was applied to determine the microbial composition of infant feces. The maternal diet was also investigated using a 24-h dietary recall.

Results

The results indicated that the fat contribu

SUBMITTER: Xi M 

PROVIDER: S-EPMC9852834 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature