Radial wall strain: a novel angiographic measure of plaque composition and vulnerability.

ABSTRACT:

Background

The lipid-to-cap ratio (LCR) and thin-cap fibroatheroma (TCFA) derived from optical coherence tomography (OCT) are indicative of plaque vulnerability.

Aims

We aimed to explore the association of a novel method to estimate radial wall strain (RWS) from angiography with plaque composition and features of vulnerability assessed by OCT.

Methods

Anonymised data from patients with intermediate stenosis who underwent coronary angiography (CAG) and OCT were analysed in a core laboratory. Angiography-derived RWS_max was computed as the maximum deformation of lumen diameter throughout the cardiac cycle, expressed as a percentage of the largest lumen diameter. The LCR and TCFA were automatically determined on OCT images by a recently validated algorithm base

SUBMITTER: Hong H 

PROVIDER: S-EPMC9853031 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature