Outcomes of non-ischaemic coronary lesions with high-risk plaque characteristics on coronary CT angiography.

ABSTRACT:

Background

The integrative implications of quantitative and qualitative plaque characteristics on clinical outcomes and therapeutic guidance have not been fully investigated.

Aims

We aimed to investigate the combined prognostic value of quantitative and qualitative plaque measures and their interactions with treatment modalities and physiological lesion severity.

Methods

Among 697 vessels from 458 patients who underwent fractional flow reserve (FFR)-guided treatment, quantitative high-risk plaque (qn-HRP; plaque burden ≥70% and minimum lumen area <3.3 mm²) and qualitative HRP (ql-HRP; low-attenuation plaque or positive remodelling) were defined on coronary computed tomography angiography (CCTA). The primary endpoint was the vessel-oriented composite outcome

SUBMITTER: Yang S 

PROVIDER: S-EPMC9853032 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature