Development and validation of a scoring system for predicting clinical coronary artery perforation during percutaneous coronary intervention of chronic total occlusions: the PROGRESS-CTO perforation score.

ABSTRACT:

Background

Coronary artery perforation is a feared complication of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) and often leads to serious adverse clinical events.

Aims

We sought to develop a risk score to predict clinical coronary artery perforation in patients undergoing CTO PCI.

Methods

We analysed clinical and angiographic parameters from 9,618 CTO PCIs in the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS-CTO). Logistic regression prediction modelling was used to identify variables independently associated with clinical perforation, and the model was internally validated with bootstrapping. Clinical coronary artery perforation was defined as any perforation requiring treatment.

Results

SUBMITTER: Kostantinis S 

PROVIDER: S-EPMC9853034 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature