Cost-effectiveness of different monitoring strategies in a screening and treatment programme for hepatitis B in The Gambia.

ABSTRACT:

Background

Clinical management of chronic hepatitis B virus (HBV) infection is complex and access to antiviral treatment remains limited in sub-Saharan Africa. International guidelines recommend monitoring at least annually for disease progression among HBV-infected people not meeting treatment criteria at initial diagnosis. This study aimed to assess the impact and cost-effectiveness of alternative strategies for monitoring.

Methods

We used a mathematical model of HBV transmission and natural history, calibrated to all available West African data, to project the population-level health impact, costs and cost-effectiveness of different monitoring strategies for HBV-infected individuals not initially eligible for antiviral treatment. We assumed that these patients were found

SUBMITTER: Schmit N 

PROVIDER: S-EPMC9853089 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature