Risk and timing of venous thromboembolism in patients with gastrointestinal cancer: a nationwide Danish cohort study.

ABSTRACT:

Aims

Cancer is a well-known risk factor of venous thromboembolism (VTE). Some cancers are believed to be more thrombogenic. The purpose of this study was to investigate the characteristics of patients with incident gastrointestinal cancers (GI) and their associated 1-year risk and timing of venous thromboembolic events and the 1-year mortality.

Methods

This study was a retrospective cohort study. Through Danish nationwide registries, all patients with first-time GI cancer diagnosis from 2008 to 2018 were identified. Incident VTE events were identified within a 1-year follow-up after GI cancer diagnosis using the Aalen-Johansen estimator. Cox proportional-hazard models were applied to investigate risk factors for VTE events and the impact of VTE on mortality.

Results

A

SUBMITTER: Tonnesen J 

PROVIDER: S-EPMC9853257 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature