Pilot study of optical coherence tomography angiography-derived microvascular metrics in hands and feet of healthy and diabetic people.

ABSTRACT: Optical coherence tomography angiography (OCTA) is a non-invasive, high-resolution imaging modality with growing application in dermatology and microvascular assessment. Accepted reference values for OCTA-derived microvascular parameters in skin do not yet exist but need to be established to drive OCTA into the clinic. In this pilot study, we assess a range of OCTA microvascular metrics at rest and after post-occlusive reactive hyperaemia (PORH) in the hands and feet of 52 healthy people and 11 people with well-controlled type 2 diabetes mellitus (T2DM). We calculate each metric, measure test-retest repeatability, and evaluate correlation with demographic risk factors. Our study delivers extremity-specific, age-dependent reference values and coefficients of repeatability of nine microvascu

SUBMITTER: Untracht GR 

PROVIDER: S-EPMC9853488 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature