The influence of resection margin width in patients with intrahepatic cholangiocarcinoma: a meta-analysis.

ABSTRACT:

Background

Some studies have pointed out that a wide resection margin can improve the prognosis of intrahepatic cholangiocarcinoma, but some researchers disagree and believe that a wide margin may increase complications. The optimal margin length of intrahepatic cholangiocarcinoma is controversial.

Method

The literature was searched in PubMed, MedLine, Embase, the Cochrane Library, and Web of Science until December 31, 2021, to evaluate the postoperative outcomes of patients with different margin width after resection. Odds ratios (ORs) with 95% confidence intervals were used to determine the effect size.

Result

A total of 11 articles were included in this meta-analysis, including 3007 patients. The narrow group had significantly lower 1-, 3-, and 5-year overall survi

SUBMITTER: Dai YS 

PROVIDER: S-EPMC9854153 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature