DNA methylome and transcriptome identified Key genes and pathways involved in Speckled Eggshell formation in aged laying hens.

ABSTRACT:

Background

The quality of poultry eggshells is closely related to the profitability of egg production. Eggshell speckles reflect an important quality trait that influences egg appearance and customer preference. However, the mechanism of speckle formation remains poorly understood. In this study, we systematically compared serum immune and antioxidant indices of hens laying speckled and normal eggs. Transcriptome and methylome analyses were used to elucidate the mechanism of eggshell speckle formation.

Results

The results showed that seven differentially expressed genes (DEGs) were identified between the normal and speckle groups. Gene set enrichment analysis (GSEA) revealed that the expressed genes were mainly enriched in the calcium signaling pathway, focal adhesion, and M

SUBMITTER: Cheng X 

PROVIDER: S-EPMC9854222 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature