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Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research-A Review.

ABSTRACT: The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based optical imaging technique that has revolutionized the diagnostic possibilities in the field of ophthalmology and has proven to be a powerful tool for many microscopic applications. Recently, OCT found its way into state-of-the-art zebrafish-based research. This review article gives an overview and a discussion of the relevant literature and an outlook for this emerging field.

SUBMITTER: Lichtenegger A

PROVIDER: S-EPMC9854701 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research-A Review.

Lichtenegger Antonia A Baumann Bernhard B Yasuno Yoshiaki Y

Bioengineering (Basel, Switzerland) 20221220 1

The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based op ...[more]

PMID: 36671577

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