Association of SRXN1 Receptor Gene Polymorphism with Susceptibility to Periodontitis.

ABSTRACT:

Background

Emerging evidence suggests that oxidative stress forms a key component in the etiopathogenesis of periodontitis. Literature evidence have shown potential antioxidants responsible for combating the pro-oxidants which stress the periodontium, but the peroxiredoxin-sulfiredoxin system is explored very minimally in periodontal disease. Thus, the present study was aimed to evaluate the genetic association of SRXN1 receptor gene polymorphism (rs6053666).

Materials and methods

A total of 100 subjects were recruited for this study, which included 50 Periodontitis patients (Stage II and above based on the criteria of American Association of Periodontology-2018) and 50 periodontally healthy or mild gingivitis. Genomic DNA was extracted from the whole blood collected from th

SUBMITTER: Murthykumar K 

PROVIDER: S-EPMC9855261 | biostudies-literature | 2022 Oct-Dec

REPOSITORIES: biostudies-literature