Selective Antibody-Free Sensing Membranes for Picogram Tetracycline Detection.

ABSTRACT: As an antibody-free sensing membrane for the detection of the antibiotic tetracycline (TC), a liquid PVC membrane doped with the ion-pair tetracycline/θ-shaped anion [3,3'-Co(1,2-C₂B₉H₁₁)₂]^- ([o-COSAN]^-) was formulated and deposited on a SWCNT modified gold microelectrode. The chosen transduction technique was electrochemical impedance spectroscopy (EIS). The PVC membrane was composed of: the tetracycline/[o-COSAN]^- ion-pair, a plasticizer. A detection limit of 0.3 pg/L was obtained with this membrane, using bis(2-ethylhexyl) sebacate as a plasticizer. The sensitivity of detection of tetracycline was five times higher than that of oxytetracycline and of terramycin, and 22 times higher than that of de

SUBMITTER: Ben Halima H 

PROVIDER: S-EPMC9855611 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature