A Competitive "On-Off-Enhanced On" AIE Fluorescence Switch for Detecting Biothiols Based on Hg²⁺ Ions and Gold Nanoclusters.

ABSTRACT: In this study, a novel "on-off-enhanced on" approach to highly sensitive rapid sensing of biothiols was developed, based on competitive modulation of gold nanoclusters (AuNCs) and Hg²⁺ ions. In our approach, the AuNCs were encapsulated into a zeolite imidazole framework (ZIF) for predesigned competitive aggregation-induced luminescence (AIE) emission. To readily operate this approach, the Hg²⁺ ions were selected as mediators to quench the fluorescence of AuNCs. Then, due to the stronger affinities between the interactions of Hg²⁺ ions with -SH groups in comparison to the AuNCs with -SH groups, the quenched probe of AuNCs@ZIF-8/Hg²⁺ displayed enhanced fluorescence after the Hg²⁺ ions were competitively interacted with -SH groups. Based

SUBMITTER: Li S 

PROVIDER: S-EPMC9856123 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature