Effect of Diet and Exercise on Knee Pain in Patients With Osteoarthritis and Overweight or Obesity: A Randomized Clinical Trial.

ABSTRACT:

Importance

Some weight loss and exercise programs that have been successful in academic center-based trials have not been evaluated in community settings.

Objective

To determine whether adaptation of a diet and exercise intervention to community settings resulted in a statistically significant reduction in pain, compared with an attention control group, at 18-month follow-up.

Design, setting, and participants

Assessor-blinded randomized clinical trial conducted in community settings in urban and rural counties in North Carolina. Patients were men and women aged 50 years or older with knee osteoarthritis and overweight or obesity (body mass index ≥27). Enrollment (N = 823) occurred between May 2016 and August 2019, with follow-up ending in April 2021.

Interventions<

SUBMITTER: Messier SP 

PROVIDER: S-EPMC9856237 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature