Outcomes Among Mechanically Ventilated Patients With Severe Pneumonia and Acute Hypoxemic Respiratory Failure From SARS-CoV-2 and Other Etiologies.

ABSTRACT:

Importance

Early observations suggested that COVID-19 pneumonia had a higher mortality rate than other causes of pneumonia.

Objective

To compare outcomes between mechanically ventilated patients with pneumonia due to COVID-19 (March 2020 to June 2021) and other etiologies (July 2016 to December 2019).

Design, setting, and participants

This retrospective cohort study was conducted at the Johns Hopkins Healthcare System among adult patients (aged ≥18 years) with pneumonia who required mechanical ventilation in the first 2 weeks of hospitalization. Clinical, laboratory, and mechanical ventilation data were extracted from admission to hospital discharge or death.

Exposures

Pneumonia due to COVID-19.

Main outcomes and measures

The primary outcome was 90-day i

SUBMITTER: Nolley EP 

PROVIDER: S-EPMC9856712 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature