Association of Developmental Language Disorder With Comorbid Developmental Conditions Using Algorithmic Phenotyping.

ABSTRACT:

Importance

Developmental language disorder (DLD) is a common (with up to 7% prevalence) yet underdiagnosed childhood disorder whose underlying biological profile and comorbidities are not fully understood, especially at the population level.

Objective

To identify clinically relevant conditions that co-occur with DLD at the population level.

Design, setting, and participants

This case-control study used an electronic health record (EHR)-based population-level approach to compare the prevalence of comorbid health phenotypes between DLD cases and matched controls. These cases were identified using the Automated Phenotyping Tool for Identifying Developmental Language Disorder algorithm of the Vanderbilt University Medical Center EHR, and a phenome enrichment analysis was

SUBMITTER: Nitin R 

PROVIDER: S-EPMC9857086 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature