Sex, Racial, and Ethnic Representation in COVID-19 Clinical Trials: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Since the onset of the COVID-19 pandemic, there have been calls for COVID-19 clinical trials to be fully representative of all demographic groups. However, limited evidence is available about the sex, racial, and ethnic representation among COVID-19 prevention and treatment trials.

Objective

To investigate whether female participants and racial and ethnic minority individuals are adequately represented in COVID-19 prevention and treatment trials in the US.

Data sources

Identified studies were registered on ClinicalTrials.gov or published in the PubMed database from October 2019 to February 2022.

Study selection

Included studies must have provided the number of enrolled participants by sex, race, or ethnicity. Only interventional studies conducted in

SUBMITTER: Xiao H 

PROVIDER: S-EPMC9857303 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature