Analysis of Time to Diagnosis and Outcomes Among Adults With Primary Hyperparathyroidism.

ABSTRACT:

Importance

Despite access to routine laboratory evaluation, primary hyperparathyroidism (PHP) remains underdiagnosed and undertreated.

Objective

To determine the consequences associated with missed diagnoses and prolonged time to diagnosis and treatment of PHP.

Design, setting, and participants

This is a retrospective cohort study of patients older than 40 years with 2 instances of hypercalcemia during 2010 to 2020 and 3 years of follow-up. Patients were recruited from 63 health care organizations in the TriNetX Research Network. Data analysis was performed from January 2010 to September 2020.

Exposures

Elevated serum calcium.

Main outcomes and measures

Existing symptoms and diagnoses associated with PHP (osteoporosis, fractures, urolithiasis, major depr

SUBMITTER: Lorenz FJ 

PROVIDER: S-EPMC9857508 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature