Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank.

ABSTRACT:

Importance

Keloids and hypertrophic scars (excessive scarring) are relatively understudied disfiguring chronic skin conditions with high treatment resistance.

Objective

To evaluate established comorbidities of excessive scarring in European individuals, with comparisons across ethnic groups, and to identify novel comorbidities via a phenome-wide association study (PheWAS).

Design, setting, and participants

This multicenter cross-sectional population-based cohort study used UK Biobank (UKB) data and fitted logistic regression models for testing associations between excessive scarring and a variety of outcomes, including previously studied comorbidities and 1518 systematically defined disease categories. Additional modeling was performed within subgroups of participants

SUBMITTER: Ung CY 

PROVIDER: S-EPMC9857738 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature